Micro-radiography of biological samples with medical contrast agents
- NázevTitle
- Micro-radiography of biological samples with medical contrast agentsMicro-radiography of biological samples with medical contrast agents
- Druh výsledkuResult type
- Článek v časopiseJournal article
- AutořiAuthors
- J. Dammer, F. Weyda, J. Beneš, V. Sopko, I. Gelbic
- DOIDOI
- 10.1016/j.nima.2013.05.168
- Časopis / citaceJournal / citation
- Nuclear Instruments and Methods in Physics Research, Section A, Accelerators, Spectrometers, Detectors and Associated Equipment. 2013, 730(730), 149-151. ISSN 0168-9002.
- RokYear
- 2013
- JazykLanguage
- eng
- WoSWoS
- 000326944100031
- ScopusScopus
- 2-s2.0-84888323422
- RIVRIV
- RIV/68407700:21670/13:00214922!RIV14-MSM-21670___
- ProjektProject
- Příprava, modifikace a charakterizace materiálů energetickým zářenímPreparation, Modification and Characterization of Materials by Energetic Radiation; Fundamentální experimenty ve fyzice mikrosvětaFundamental Experiments in Physics of Microworld; Využití radionuklidů a ionizujícího zářeníApplication of Rradionuclides and Iionising Rradiation
AbstraktAbstract
Micro-radiography is an imaging technique that uses X-rays to study the internal structures of objects. This fast and easy imaging tool is based on differential X-ray attenuation by various tissues and structures within biological samples. The experimental setup described is based on the semiconductor pixel X-ray detector Medipix2 and X-ray micro-focus tube. Our micro-radiographic system has been recently used not only for the examination of internal structures of various arthropods and other biological objects but also for tracing some processes in selected model species (we used living larvae of mosquito Culex quinquefasciatus). Low concentrations of iodine, lanthanum or gold particles were used as a tracer (contrast agent). Such contrast agents increase the absorption of X-rays and allow a better visibility of internal structures of model organisms (especially the various cavities, pores, etc.). In addition, the movement of tracers in selected timing experiments demonstrates some physiological functions of digestive and excretory system.
Micro-radiography is an imaging technique that uses X-rays to study the internal structures of objects. This fast and easy imaging tool is based on differential X-ray attenuation by various tissues and structures within biological samples. The experimental setup described is based on the semiconductor pixel X-ray detector Medipix2 and X-ray micro-focus tube. Our micro-radiographic system has been recently used not only for the examination of internal structures of various arthropods and other biological objects but also for tracing some processes in selected model species (we used living larvae of mosquito Culex quinquefasciatus). Low concentrations of iodine, lanthanum or gold particles were used as a tracer (contrast agent). Such contrast agents increase the absorption of X-rays and allow a better visibility of internal structures of model organisms (especially the various cavities, pores, etc.). In addition, the movement of tracers in selected timing experiments demonstrates some physiological functions of digestive and excretory system.