Ústav technické a experimentální fyziky Institute of Experimental and Applied Physics

X-ray micro-CT scanner for small animal imaging based on Timepix detector technology

NázevTitle
X-ray micro-CT scanner for small animal imaging based on Timepix detector technologyX-ray micro-CT scanner for small animal imaging based on Timepix detector technology
Druh výsledkuResult type
Článek v časopiseJournal article
AutořiAuthors
J. Dudák, J. Žemlička, F. Krejčí, Š. Polanský, J. Jakůbek, JM Mrzílková, MP Patzelt, JT Trnka
DOIDOI
10.1016/j.nima.2014.10.076
Časopis / citaceJournal / citation
Nuclear Instruments and Methods in Physics Research, Section A, Accelerators, Spectrometers, Detectors and Associated Equipment. 2015, 773 81-86. ISSN 0168-9002.
RokYear
2015
JazykLanguage
eng
WoSWoS
000346827700012
ScopusScopus
2-s2.0-84918779214
RIVRIV
RIV/68407700:21670/15:00227715!RIV16-MK0-21670___
ProjektProject
Materiálový výzkum pro InovaSEEDMaterials Research for InovaSEED; Nová mobilní zařízení, laboratoř a metodika pro nedestruktivní materiálovou analýzu výtvarného umění v kontextu ochrany kulturního dědictvíNew portable instruments, laboratory and methodology for the non-destructive materials analysis of the fine art in the frame of cultural heritage protection

AbstraktAbstract

We describe a newly developed compact micro-CT scanner with rotating gantry equipped with a Timepix Quad hybrid pixel semiconductor detector and a micro-focus X-ray tube providing spatial resolution down to 30 µm. The resolving power of the device in relation to soft tissue sensitivity is demonstrated using a tissue-equivalent phantom and different types of biological samples. The results demonstrate that the use of noiseless particle counting detectors is a promising way to achieve sufficient soft tissue contrast even without any contrast agents.

We describe a newly developed compact micro-CT scanner with rotating gantry equipped with a Timepix Quad hybrid pixel semiconductor detector and a micro-focus X-ray tube providing spatial resolution down to 30 µm. The resolving power of the device in relation to soft tissue sensitivity is demonstrated using a tissue-equivalent phantom and different types of biological samples. The results demonstrate that the use of noiseless particle counting detectors is a promising way to achieve sufficient soft tissue contrast even without any contrast agents.