Application of detector TIMEPIX for Multimodal Imaging MRI-SPECT
- NázevTitle
- Application of detector TIMEPIX for Multimodal Imaging MRI-SPECTApplication of detector TIMEPIX for Multimodal Imaging MRI-SPECT
- Druh výsledkuResult type
- Kvalifikační práceThesis
- AutořiAuthors
- J. Zajíček, L. Šefc, J. Kozempel, I. Štekl
- Časopis / citaceJournal / citation
- Praha: Defense date 2018-09-18. PhD Thesis. CTU IEAP. Department of Experimental Physics. Supervised by I. ŠTEKL.
- RokYear
- 2018
- JazykLanguage
- eng
- RIVRIV
AbstraktAbstract
This work investigates in detail the application of hybrid semiconductor detector Timepix in combination with Magnetic Resonance for purposes of multimodal medical imaging. It deals with design and construction of the experimental apparatus - insert system capable to fully operate in high magnetic field with magnetic induction of 4.7 Tesla. It describes construction of system components (Printed Circuit Board for CdTe sensors, Radiofrequency coil, MRI-compatible collimators, phantoms, etc.) including of software development for SPECT back projection and fusing of images MRI and SPECT into one single image containing both anatomical and functional information. Measurements were performed on a specially prepared phantoms made from gelatine using of CdTe sensors and radioisotopic sources (57Co 122 keV γ ray; 99mTc 140.5 keV γ ray) inside my-own built RF coil by Bruker BioSpec 47/20 MR animal scanner. In terms of further development work explores the possibilities and problems of simultaneous operation of methods MRI and SPECT.
This work investigates in detail the application of hybrid semiconductor detector Timepix in combination with Magnetic Resonance for purposes of multimodal medical imaging. It deals with design and construction of the experimental apparatus - insert system capable to fully operate in high magnetic field with magnetic induction of 4.7 Tesla. It describes construction of system components (Printed Circuit Board for CdTe sensors, Radiofrequency coil, MRI-compatible collimators, phantoms, etc.) including of software development for SPECT back projection and fusing of images MRI and SPECT into one single image containing both anatomical and functional information. Measurements were performed on a specially prepared phantoms made from gelatine using of CdTe sensors and radioisotopic sources (57Co 122 keV γ ray; 99mTc 140.5 keV γ ray) inside my-own built RF coil by Bruker BioSpec 47/20 MR animal scanner. In terms of further development work explores the possibilities and problems of simultaneous operation of methods MRI and SPECT.