ÚTEFČVUT Ústav technické a experimentální fyziky ČVUT v PrazeInstitute of Experimental and Applied Physics, CTU in Prague

Application of detector TIMEPIX for Multimodal Imaging MRI-SPECT

NázevTitle
Application of detector TIMEPIX for Multimodal Imaging MRI-SPECTApplication of detector TIMEPIX for Multimodal Imaging MRI-SPECT
Druh výsledkuResult type
Kvalifikační práceThesis
AutořiAuthors
J. Zajíček
Vedoucí, konzultanti, oponentiSupervisors, advisors, reviewers
L. Šefc, J. Kozempel, I. Štekl
Časopis / citaceJournal / citation
Praha: Defense date 2018-09-18. PhD Thesis. CTU IEAP. Department of Experimental Physics. Supervised by I. ŠTEKL.
RokYear
2018
JazykLanguage
eng
Citace ke staženíDownload citation
TXT · BibTeX

AbstraktAbstract

This work investigates in detail the application of hybrid semiconductor detector Timepix in combination with Magnetic Resonance for purposes of multimodal medical imaging. It deals with design and construction of the experimental apparatus - insert system capable to fully operate in high magnetic field with magnetic induction of 4.7 Tesla. It describes construction of system components (Printed Circuit Board for CdTe sensors, Radiofrequency coil, MRI-compatible collimators, phantoms, etc.) including of software development for SPECT back projection and fusing of images MRI and SPECT into one single image containing both anatomical and functional information. Measurements were performed on a specially prepared phantoms made from gelatine using of CdTe sensors and radioisotopic sources (57Co 122 keV γ ray; 99mTc 140.5 keV γ ray) inside my-own built RF coil by Bruker BioSpec 47/20 MR animal scanner. In terms of further development work explores the possibilities and problems of simultaneous operation of methods MRI and SPECT.

This work investigates in detail the application of hybrid semiconductor detector Timepix in combination with Magnetic Resonance for purposes of multimodal medical imaging. It deals with design and construction of the experimental apparatus - insert system capable to fully operate in high magnetic field with magnetic induction of 4.7 Tesla. It describes construction of system components (Printed Circuit Board for CdTe sensors, Radiofrequency coil, MRI-compatible collimators, phantoms, etc.) including of software development for SPECT back projection and fusing of images MRI and SPECT into one single image containing both anatomical and functional information. Measurements were performed on a specially prepared phantoms made from gelatine using of CdTe sensors and radioisotopic sources (57Co 122 keV γ ray; 99mTc 140.5 keV γ ray) inside my-own built RF coil by Bruker BioSpec 47/20 MR animal scanner. In terms of further development work explores the possibilities and problems of simultaneous operation of methods MRI and SPECT.

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