BrachyView: multiple seed position reconstruction and comparison with CT post-implant dosimetry
- NázevTitle
- BrachyView: multiple seed position reconstruction and comparison with CT post-implant dosimetryBrachyView: multiple seed position reconstruction and comparison with CT post-implant dosimetry
- Druh výsledkuResult type
- Článek v časopiseJournal article
- AutořiAuthors
- S. Alnaghy, K.J. Loo, D.L. Cutajar, S. Pospíšil
- Klíčová slovaKeywords
- X-ray detector
- DOIDOI
- 10.1088/1748-0221/11/05/P05002
- Časopis / citaceJournal / citation
- Journal of Instrumentation 11(05), P05002-P05002 (2016) · ISSN 1748-0221
- RokYear
- 2016
- JazykLanguage
- eng
- ZáznamyRecords
- ProjektProject
- Institucionální podpora na rozvoj výzkumné org.Institucionální podpora na rozvoj výzkumné org.
- CitovánoCited by
- 5 (OpenAlex)
- Citace ke staženíDownload citation
- TXT · BibTeX
AbstraktAbstract
BrachyView is a novel in-body imaging system utilising high-resolution pixelated silicon detectors (Timepix) and a pinhole collimator for brachytherapy source localisation. Recent studies have investigated various options for real-time intraoperative dynamic dose treatment planning to increase the quality of implants. In a previous proof-of-concept study, the justification of the pinhole concept was shown, allowing for the next step whereby multiple active seeds are implanted into a PMMA phantom to simulate a more realistic clinical scenario. In this study, 20 seeds were implanted and imaged using a lead pinhole of 400 μ m diameter. BrachyView was able to resolve the seed positions within 1–2 mm of expected positions, which was verified by co-registering with a full clinical post-implant CT scan.
BrachyView is a novel in-body imaging system utilising high-resolution pixelated silicon detectors (Timepix) and a pinhole collimator for brachytherapy source localisation. Recent studies have investigated various options for real-time intraoperative dynamic dose treatment planning to increase the quality of implants. In a previous proof-of-concept study, the justification of the pinhole concept was shown, allowing for the next step whereby multiple active seeds are implanted into a PMMA phantom to simulate a more realistic clinical scenario. In this study, 20 seeds were implanted and imaged using a lead pinhole of 400 μ m diameter. BrachyView was able to resolve the seed positions within 1–2 mm of expected positions, which was verified by co-registering with a full clinical post-implant CT scan.