Ústav technické a experimentální fyziky Institute of Experimental and Applied Physics

The scope of detector Medipix2 in micro-radiography of biological samples

NázevTitle
The scope of detector Medipix2 in micro-radiography of biological samplesThe scope of detector Medipix2 in micro-radiography of biological samples
Druh výsledkuResult type
Článek v časopiseJournal article
AutořiAuthors
J. Dammer, F. Weyda, J. Jakůbek, P. Skrabal, V. Sopko, D. Vavřík
DOIDOI
10.1016/j.nima.2010.06.159
Časopis / citaceJournal / citation
Nuclear Instruments and Methods in Physics Research, Section A, Accelerators, Spectrometers, Detectors and Associated Equipment. 2011, 2011(633), 171-172. ISSN 0168-9002.
RokYear
2011
JazykLanguage
eng
WoSWoS
000292782400053
ScopusScopus
2-s2.0-79959850879
RIVRIV
RIV/68407700:21670/11:00188840!RIV12-MSM-21670___
ProjektProject
Fundamentální experimenty ve fyzice mikrosvětaFundamental Experiments in Physics of Microworld; Využití radionuklidů a ionizujícího zářeníApplication of radionuclides and ionising radiation

AbstraktAbstract

We present our experimental setup devoted to high resolution X-ray micro-radiography that is suitable for imaging of small biological samples. The photon source is a FeinFocus micro-focus X-ray tube. The single photon counting pixel device Medipix2 serves as imaging area. Recently used imaging detectors as radiography films or scintillator detectors, cannot visualize required information about inner structure of scanned sample. Detectors Medipix2 do not suffer from so called dark current noise and work in unlimited dynamic range. These features of detectors confer high quality and high contrast of final images. The radiographic imaging with detectors Medipix2 represents non-invasive and non-destructive method of investigation. Hereby, we demonstrate results of micro-radiographic study of internal structures of tiny biological samples. In addition to morphological and anatomical studies, we would like to present preliminary study of dynamic processes inside of organisms using micro-radiographic video-capturing.

We present our experimental setup devoted to high resolution X-ray micro-radiography that is suitable for imaging of small biological samples. The photon source is a FeinFocus micro-focus X-ray tube. The single photon counting pixel device Medipix2 serves as imaging area. Recently used imaging detectors as radiography films or scintillator detectors, cannot visualize required information about inner structure of scanned sample. Detectors Medipix2 do not suffer from so called dark current noise and work in unlimited dynamic range. These features of detectors confer high quality and high contrast of final images. The radiographic imaging with detectors Medipix2 represents non-invasive and non-destructive method of investigation. Hereby, we demonstrate results of micro-radiographic study of internal structures of tiny biological samples. In addition to morphological and anatomical studies, we would like to present preliminary study of dynamic processes inside of organisms using micro-radiographic video-capturing.